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Skeptics Fear Human Genome
'Book of Life' Could
Spell Death
By Lyndsay Griffiths
http://dailynews.yahoo.com/h/nm/20000626/sc/genome_ethics_dc_1.html
6-26-00
 
 
LONDON (Reuters) - Scientists heralded a brave new world Monday but skeptics said a genetic breakthrough could usher in a sinister era of perfect people and death to the disabled.
 
``The further science goes, the further the worst case scenario goes,'' Steve Jenkins, a spokesman for the Church of England, told Reuters. ``I'm not anti-science but there is no way that God is now out of a job.''
 
He spoke after an international team of researchers said they had mapped 97 percent of the human genome -- the genetic makeup of the human body -- in a scientific accomplishment on a par with the discovery of penicillin or the lunar landing.
 
``This is the outstanding achievement not only of our lifetime but in terms of human history,'' said Dr Michael Dexter, whose Wellcome Trust funded the British arm of the project.
 
Carried out in 16 centers around the globe, the researchers have effectively whittled down the human body to a complex string of letters that should revolutionize the way doctors see the body and treat its shortfalls.
 
The potential benefits are huge: drugs tailor-made for individuals, predictive testing, improved understanding of disease along with gene therapy to put in-built wrongs to right.
 
Others fear the possible misuse of science in man's drive to create a perfect world and say few will benefit.
 
``It's the difference between using genetics to correct something that has gone wrong and using them to create something considered perfect,'' said Jenkins, who trained in science. ''The idea of designing humans from scratch along with the prospect of an enormous increase in abortion is not the world we want.''
 
While the scientists emphasized their so-called ``book of life'' was just the beginning of a long road ahead, doubters said it would benefit few and could turn out to be a giant step back to the sort of eugenics practiced in Nazi Germany.
 
BLOND OR BRUNETTE, MADAME?
 
``Mapping the human genome is a great human achievement,'' Richard Nicholson, editor of the Bulletin of Medical Ethics, said. ``Like climbing Mount Everest, it will benefit few people, leaving most untouched. But unlike climbing Mount Everest, it has the potential to damage large numbers of people.''
 
Designer babies could be created, flawed fetuses killed.
 
The stigma of being anything less than perfect could soar.
 
``Disabled people feel a responsibility to raise the alarm,'' said Agnes Fletcher of the Royal Association for Disability and Rehabilitation. ``'New hope' for disabled people is accompanied by the danger of disabled people and others experiencing increased discrimination in employment, insurance, healthcare provision and education.''
 
U.S. lawmakers have already raised the alarm about medical insurers screening out high-risk groups and employers passing over genetically flawed staff.
 
``Social policy must keep pace with science. The abuse of genetic information must be prevented,'' said New York Democrat Louise Slaughter, who is pushing for a bill to outlaw genetic discrimination.
 
Yet scientists say they are a long way from making sense of their new alphabet soup and putting it to practical use. They point out that the anatomy of the heart was worked out in 1543, while the first heart transplant did not come until 1967.
 
New Scientists Up To Old Tricks
 
Yet man has been dabbling in eugenics for centuries.
 
Plato's Republic depicts a society chasing self-improvement through selective breeding while references to eugenic ideals appear as far back as the Old Testament.
 
English statistician Francis Galton took it further in 1869 by proposing a system of arranged marriages between men of distinction and women of wealth to produce a gifted race.
 
Indeed it was Galton who coined the term ``eugenics,'' and the American Eugenics Society took up his baton in 1926 by proposing restrictions on immigrants from ``inferior'' stock, along with sterilization for the insane, retarded and epileptic.
 
The German Nazi party of the 1930s went to the wildest extremes, using eugenics to justify its attempted extermination of European Jews and other groups of people.



 
 
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