- Jeff - There is not only the potential for some nutritional
supplements as a vector for CJD/TSE but another major factor is the vaccine
issue as a route for death via CJD/TSE. I worked on this data for over
a year and I am telling you straight: they have been covering this up for
30 or 40 years. Most of this data I was able to acquire through FOIAs in
both the UK and the US before the BSE-Inquiry became public - after which
both governments made most of the documents secret. But that's another
story, one I am not finished with yet ;-). Here we go...
- ---- Original Message ----
- Subject: Re: Adverse events associated with dietary supplements:
- an observational study
- From: Terry S. Singeltary Sr email@example.com
- To: firstname.lastname@example.org, email@example.com
- CC: firstname.lastname@example.org, email@example.com,
- firstname.lastname@example.org, email@example.com,
- Date: Mon, 13 Jan 2003
- Re: Adverse events associated with dietary supplements:
- an observational study
- JANUARY 11, 2003
- Greetings to the Lancet and Authors of this article,
I hope you don't mind me writing this lengthy letter.
- This article and its warning was a long time coming for
the supplement industry and the dangers some of its products pose to human
- Some of these supplements make claims which under no
circumstances could they be true. However, what I find most disturbing
is that there were no warnings of the potential for transmission to humans
of TSEs from some of these nutritional supplements which contain animal
organs and some containing the most high risk SRMs (specified risk materials)
that could transmit TSEs to humans. Again, I think your article should
have mentioned this most disturbing fact.
- There have been documented cases of humans taking supplements
containing animal organs who subsequently died from CJD. Of course, with
no testing to date to confirm the source and route of transmission, it
is impossible to confirm this. Also, the incubation period makes it very
difficult to trace route and source.
- However, with the KNOWN transmission studies to date
>from TSEs, and the fact that all the world's cattle that came down
with BSE were ingesting a nutritional supplement to super-ovulate cattle.
(Not to forget about the potential for some BSE cases to come from vaccinations
containing pituitary-derived SRMs.)
- TWA LITTLE minute
- COMMERCIAL IN CONFIDENCE
- NOT FOR PUBLICATION
- NON-LICENSED HUMAN TISSUE DEVICES WERE NOT COMMERCIALLY
- I was quite prepared to believe in unofficial pituitary
hormones, also in the 1970's, whether as described by Dr. Little, or in
other circumstances, for animal use.
- The fact that there were jars of pituitaries (or extract)
around on shelves is attested by the still potent 1943 pituitaries, described
in Stockell Hartree et al. (J/RF/17/291) which had come from the lab. at
Mill Hill. Having taken the trouble to collect them, they were not lightly
- more on the 1968 medicine act, they forgot to follow
- Draft cover letter to product licence holders (considered
by Human and Vet Medicines including deer)
- (It was noted with concern that hormone extracts could
be manufactured by a veterinary surgeon for administration to animals under
his care without any Medicines Act Control.)
- < FONT SIZE=+1>http://www.bseinquiry.gov.uk/files/yb/1988/06/08011001.pdf
- TWA LITTLE STATEMENT 331
- Date: Sun, 12 Jan 2003 12:56:44 -0600
- Sender: Bovine Spongiform Encephalopathy
- From: "Terry S. Singeltary Sr."
- Subject: Re: USA ruminant-to-ruminant feed ban warning
- With these known facts about nutritional supplements,
I think it imperative to include this potential route and source of TSE
and warning in this article.
- Why was it not included? I lost my mother to hvCJD DOD
12/14/97, and I probably will not live long enough to know the route and
source of her TSE. Exactly one year previously, to the day 12/14/96, my
neighbor also lost his mother to sporadic CJD. Both of these cases were
confirmed. but my neighbor's mother had been taking a nutritional supplement
called IPLEX, made by Standard Process Co.
- Here is a listing of potentially TSE-tainted tissues:
- vacuum dried bovine BRAIN, bone meal, bovine EYE, veal
bone, bovine liver powder, bovine adrenal, vacuum dried bovine kidney,
and vacuum dried porcine stomach.
- The CDC came and took the pills, a few years later, I
spoke with the late Dr. Gibbs and NIH/CDC and he told me that those particular
pills did not show any infectivity with the testing techniques to date,
but he also told me -
- 1. That the testing techniques at that time may not be
sufficient to pick up any 'low-level' infectivity. (so, if accumulation
plays into this, this could play a big part).
- 2. She had been taking these type pills for years, could
have been another batch.
- There have been other people die of CJD that were taking
these type nutritional supplements.
- So, my point being, I believe this to warrant a potential
risk factor, one not to be ignored, especially in the USA where there are
many known TSEs, and where there are many unknowns due to the lack of sufficient
TSE testing in USA cattle, and especially since the new findings of Collinge
et al, where BSE transmission to the 129-methionine genotype can lead to
an alternate phenotype which is indistinguishable from type 2 PrPSc, the
commonest sporadic CJD.
- I believe these findings to be of substantial importance:
- DEPARTMENT OF HEALTH AND HUMAN SERVICES
- FOOD AND DRUG ADMINISTRATION
- CENTER FOR BIOLOGICS EVALUATION AND RESEARCH
- TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES ADVISORY COMMITTEE
- Friday, January 19, 2001
- Holiday Inn Bethesda Versailles I and II
- 8120 Wisconsin Avenue Bethesda, Maryland
- 2 PARTICIPANTS
- Paul W. Brown, M.D., Chairperson
- William Freas, Ph.D., Executive Secretary
- VOTING MEMBERS
- Ermias D. Belay, M.D. David C. Bolton, Ph.D. Donald S.
- Dean O. Cliver, Ph.D.
- Bruce M. Ewenstein, M.D., Ph.D. Peter G. Lurie, M.D.
- M.D. Stanley B. Prusiner, M.D. Raymond P. Roos, M.D.
- Williams, D.V.M., Ph.D.
- VOTING CONSULTANTS
- Linda A. Detwiler, D.V.M.
- David Gaylor, Ph.D.
- Paul R. McCurdy, M.D.
- Kenrad E. Nelson, M.D.
- NONVOTING CONSULTANT
- Susan Leitman, M.D.
- Richard Davey, M.D. Louis Katz, M.D.
- page 501
- 1 DR. BOLTON: I have an additional question about
- 2 that. What is the assurance that additional locally
- 3 tracheas are not added into that manufacturing process,
- 4 boosting the yield, if you will, but being returned
- 5 U.S. as being produced from U.S.-sourced raw material?
- 6 DR. McCURDY: Are there data to indicate how many
- 7 grams, or whatever, of infected brain are likely to
- 8 an organism, either animal or man, when taken orally?
- 9 DR. BROWN: If I am not mistaken, and I can be
- 10 corrected, I think a half a gram is enough in a cow,
- 11 in other words, one good dietary-supplement pill.
- 12 DR. McCURDY: What I am driving at is the question
- 13 we are asked is really not do we wish to regulate
- 14 things coming in. I think the statements about difficulties
- 15 in regulating things in the future or near future
- 16 regulations were probably accurate.
- 17 But I think that we could exhibit some quite
- 18 reasonable concern about blood donors who are taking
- 19 supplements that contain a certain amount of unspecified-
- 20 origin brain, brain-related, brain and pituitary material.
- 21 If they have done this for more than a sniff or something
- 22 like that, then, perhaps, they should be deferred
- 23 donors.
- 24 That is probably worse than spending six months in
- 25 the U.K.
- 3681t2.rtf(845) page 501
- There has been a Nutritional Supplement mad cow warning
letter circulating around since about 1990. Every year they issue the same
letter to the manufactures asking them to please be sure they source their
products from BSE-FREE countries. but we all know, the statement BSE-FREE,
is a joke, especially in the USA. I sat in on the 50 state emergency BSE
conference call, (uninvited guest) and I know for a fact the so-called
'pharmaceutical grade' bovine source herds, bovines that were to never
be fed ruminant materials, the USA cannot for certain say that indeed these
cattle have never ingested ruminant feed, in fact, some probably had.
- Subject: BSE--U.S. 50 STATE CONFERENCE CALL Jan. 9, 2001
- Date: Tue, 9 Jan 2001 16:49:00 -0800
- From: "Terry S. Singeltary Sr." <firstname.lastname@example.org>
- Reply-To: Bovine Spongiform Encephalopathy <BSE-L@uni-karlsruhe.de>
- To: BSE-L@uni-karlsruhe.de
- Bovine Spongiform Encephalopathy
- Greetings List Members,
- I was lucky enough to sit in on this BSE conference call
today and even managed to ask a question. that is when the trouble started.
- I submitted a version of my notes to Sandra Blakeslee
of the New York Times, whom seemed very upset, and rightly so.
- "They tell me it is a closed meeting and they will
release whatever information they deem fit. Rather infuriating."
- And I would have been doing just fine, until I asked
my question. I was surprised my time to ask a question came so quickly.
- (understand, these are taken from my notes for now. the
spelling of names and such could be off.)
- [host Richard Barns]
- And now a question from Terry S. Singeltary of CJD Watch.
- Yes, Thank You. U.S. cattle - what kind of guarantee
can you give for serum or tissue donor herds?
- [no answer, you could hear in the background, mumbling
and "We can't. Have him ask the question again."]
- [host Richard]
- Could you repeat the question?
- U.S. cattle..what kind of guarantee can you give for
serum or tissue donor herds?
- [not sure whom ask this]
- What group are you with?
- CJD Watch, my Mom died from hvCJD and we are tracking
- [not sure who is speaking]
- Could you please disconnect Mr. Singeltary