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Another Mystery Enterovirus
Kills Children In Vietnam
From Patricia Doyle, PhD
dr_p_doyle@hotmail.com
4-11-3
 
Hello Jeff: I think it is a little to soon to make a determination that the mystery enterovirus is unrelated to SARS. This is just amazing. Yet, again, another mystery virus emerges.
 
Patricia
 
From ProMED-mail promed@promedmail.org
 
Vietnam: Suspected Enterovirus Involvement In Childhood Deaths
 
(Reuters) -- At least 10 Vietnamese children aged under 3 years have died in the past month from an unidentified virus that is suspected to belong to the enterovirus group, state-run media reported on Tue 8 Apr 2003. The cases are believed to be unrelated to the flu-like severe acute respiratory syndrome (SARS) that has swept through many countries, killing 4 medical workers in Vietnam.
 
The Tuoi Tre (Youth) newspaper said the 10 deaths were reported among 11 children admitted into Ho Chi Minh City's Children Hospital One. They all had high fever, diarrhea, fell into comas, and developed respiratory and heart failure. The latest death on Monday was of a 16-month-old child who died 11 hours after being admitted. Doctors were working to identify the virus that they suspected may belong to the 'enterovirus' group, which infects the intestines and causes paralysis, vomiting, and diarrhea, the paper said. It quoted Dr. Tang Chi Thuong, the hospital deputy director, as saying the patients did not respond to resuscitation efforts and died quickly. Tests for known viruses, including the one that causes Japanese encephalitis, were negative, he said. Officials and doctors at the hospital declined comment.
 
The first death from the mystery illness occurred in early March 2003 in the same hospital in Vietnam's largest city, which has a population of 7 million people. Enterovirus killed 50 children and hospitalized another 253 in Taiwan in 1998, and deaths from the disease were also reported in Australia in 1999.
 
----- ProMED-mail <promed@promedmail.org
 
[An extensive outbreak of Human enterovirus 71 infection was reported in Sarawak in February 2003 (see: Human enterovirus 71 - Malaysia (Sarawak) 20030403.0815). The molecular epidemiology reported by Dr. Cardosa and colleagues suggested that a new variant (sub-genogroup) of Human enterovirus 71 may spreading in the Asia-Pacific region. Human enterovirus 71 infection is associated normally with hand, foot and mouth disease in children, but occasionally can be responsible for neurological disease in an appreciable number of children. Human enterovirus 71 was responsible for the outbreak in Taiwan in 1998 referred to above, and presumably the same virus is suspected as the cause of the current outbreak in Vietnam. A precise diagnosis is awaited. - Mod.CP]
 
 
Patricia A. Doyle, PhD Please visit my "Emerging Diseases" message board at: http://www.clickitnews.com/emergingdiseases/index.shtml Zhan le Devlesa tai sastimasa Go with God and in Good Health
 
 
From Patricia Doyle, PhD
4-11-3
 
Hello Jeff...
 
Regaring the Mystery novel enterovirus that is killing children in Viet Nam:
 
Thought this was interesting, although I do not know where it fits in the puzzle. Nonpolio entero, second only to the common cold as the most common viral infectious agent. Hum? Where have we heard that before? I still wonder what the Polio stock virus audit showed. How much polio virus stocks are missing? Patricia
 
Non-Polio Enterovirus Infections
 
What are enteroviruses? Enteroviruses are small viruses that are made of ribonucleic acid (RNA) and protein. This group includes the polioviruses, coxsackieviruses, and echoviruses. In addition to the three different polioviruses, there are 61 non-polio enteroviruses that can cause disease in humans: 23 Coxsackie A viruses, 6 Coxsackie B viruses, 28 echoviruses, and 4 other enteroviruses.
 
How common are infections with these viruses?
 
Non-polio enteroviruses are second only to the "common cold" viruses, the rhinoviruses, as the most common viral infectious agents in humans. The enteroviruses cause an estimated 10-15 million or more symptomatic infections a year in the United States. All three types of polioviruses have been eliminated from the Western Hemisphere by the widespread use of vaccines.
 
 
 
Patricia A. Doyle, PhD Please visit my "Emerging Diseases" message board at: http://www.clickitnews.com/emergingdiseases/index.shtml Zhan le Devlesa tai sastimasa Go with God and in Good Health


 

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