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Mononucleosis Doubles Risk
Of Hodgkin's Disease

The Globe and Mail
10-2-3


Young adults who get mononucleosis, the "kissing disease," have more than double the risk of developing a rare type of cancer, a Danish study found.
 
Doctors have long suspected a link between mononucleosis and Hodgkin's disease, a highly treatable cancer of the lymph system. But the role played by the common virus that causes mono was uncertain. The virus, Epstein-Barr, is found in about one-third of Hodgkin's tumours.
 
In a study of over 63,000 young adults suspected of having mono, the researchers found that those who got mono had a higher-than-average chance of getting Hodgkin's, and the risk lasted for two decades. There was no increased risk for those who did not have mono.
 
"I think it removes the last shade of doubt that the virus actually has something to do with causing Hodgkin's disease," said Dr. Richard Ambinder of Johns Hopkins School of Medicine, who was not involved in the research. "The flip side to that is that everyone's got the virus, so it can't possibly be the whole story."
 
The Danish researchers stressed that Hodgkin's disease, also known as Hodgkin's lymphoma, is uncommon. About one in 1,000 of young adults with mono will get the cancer, they said.
 
"Only in rare circumstances will this lead to the development of Hodgkin's lymphoma. So there's no reason for any panic," said Dr. Mads Melbye, one of the researchers at Statens Serum Institut, the Danish equivalent of the U.S. Centers for Disease Control and Prevention.
 
The study is reported in Thursday's New England Journal of Medicine.
 
© 2003 Bell Globemedia Publishing Inc. All Rights Reserved.
 
http://www.globeandmail.com/servlet/story/RTGAM.20031001.whodg1001/BNStory/International/

 

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