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CJD Fears Prompt Ban On
Thousands Of UK Blood Donors

By Jeremy Laurance
Health Editor
The Independent - UK
3-16-4


Thousands of people who have received blood transfusions over the last two decades are to be banned from giving blood because of fears that they could transmit vCJD, the human form of BSE.
 
John Reid, the Health Secretary, said the ban was a precautionary measure to avoid the "slight risk" of transmission of the disease after a suspected case of a patient who was thought to have caught vCJD from a transfusion. About 52,000 donors will be excluded from the 1.7 million who regularly give blood. Mr Reid said the move would "inevitably lead to a reduction in the supply of blood available for transfusions".
 
The case that led to the ban was announced in December and involved a patient who died of vCJD last autumn. The patient is believed to have acquired the disease after a blood transfusion in 1996 from a donor who later developed vCJD.
 
The donor died in 1999, confirming doctors' fears that the incurable brain disease, which can be passed to humans through consumption of BSE-infected cattle, could also be transmitted through blood. The donor had shown no sign of infection at the time of the donation.
 
Experts said at the time that a coincidence could not be ruled out, but the chances of the donor and recipient independently falling victim to the brain disease were remote. Mr Reid insisted yesterday that this was still a "possibility, not a proven causal connection".
 
Fifteen other people who received blood from donors and later developed vCJD had been identified and contacted, a Health Department spokesman said. The risks had been explained to them and they had been offered counselling.
 
There are potentially thousands more people who have been treated with blood plasma products and could face a much smaller risk.
 
The spokesman said that everyone who had ever eaten beef was at potential risk of developing vCJD but people who had received blood transfusions had an additional potential source of infection.
 
One of the unanswered questions is how long a person could be infectious and capable of passing on the disease before symptoms develop. There is no screening test for vCJD but post-mortem examinations have revealed signs of the disease in body tissues such as tonsils and appendixes several years before symptoms started.
 
Announcing the ban in the Commons, Mr Reid told MPs that the Government was following a "highly precautionary" approach. He said: "Although people may have concerns about the implications of this announcement, I would emphasise again that this action is being taken because of an uncertain but slight risk.
 
"People should, indeed, continue to have a blood transfusion when it is really necessary. Any slight risk associated with receiving blood must be balanced against the significant risk of not receiving that blood when it is most needed."
 
The ban would apply to anyone who received a transfusion after January 1980 because it was "generally accepted that there would have been no exposure to BSE in the UK before that date", Mr Reid said. He urged people able to donate blood to continue to do so.
 
Measures will be put in place to help compensate for the thousands of banned donors. Mr Reid said transfusions should only be done where there was a "clear clinical need".
 
Some experts called for more radical action. Sheila Bird, a professor of statistics at the Medical Research Council at Cambridge, said tonsils removed in operations and post- mortem examinations should be tested for traces of abnormal prions so checks could be made on whether people had given blood and instruments used in surgery could be destroyed.
 
She said: "Banning people who have had transfusions from becoming blood donors is an important first step but it is not the only thing we can do."
 
© 2004 Independent Digital (UK) Ltd
 
http://news.independent.co.uk/uk/health/story.jsp?story=501975




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