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$40 Million To CSU
For Bioterror Research
From Patricia Doyle, PhD
dr_p_doyle@hotmail.com
6-7-5
 
Hello Jeff - My thanks to a poster to my clickitnews Emerging Diseases message board for this important story.
 
This is the second one in the last month.
There's one in Texas recently, too - BioSafety Level 4
 
Patty
 
 
CSU Is Awarded $40 Million Grant
Funds For Research On Bioterrorism, Disease
 
By Jim Erickson
Rocky Mountain News
6-2-5
 
Colorado State University was awarded a four-year, $40 million federal grant Wednesday to develop treatments and vaccines for bioterrorism agents and infectious diseases, such as plague and hantavirus.
 
The grant from the National Institute of Allergy and Infectious Diseases is the largest single research award in the school's history. It will establish a regional center for the study of animal diseases that can affect humans - so-called zoonotic diseases.
 
One major goal is to get new diagnostic tests, treatments and vaccines to market quickly by encouraging partnerships between university researchers and industry, said CSU microbiologist Barry Beaty.
 
"We're going to have the facilities and the know-how to move discovery into usable products in a hurry," said Beaty, who will lead the Rocky Mountain Regional Center of Excellence.
 
The new center is not a building.
 
It is a research consortium including five other universities, federal laboratories, small business partners, and hospitals in the Rocky Mountain region.
 
Consortium members will study various pathogens at a $22 million biocontainment laboratory to be built on CSU's Foothills Campus, west of downtown Fort Collins.
 
Groundbreaking for that project, which is funded mainly by a $16.6 million NIAID grant, is expected within a year.
 
Wednesday's $40 million grant will pay for the research to be done at the new lab. The funds will pay for laboratory equipment, researchers' salaries and supplies, among other things.
 
The new lab will be a Biosafety Level 3 facility.
 
Infectious disease labs are designated by biosafety levels 1 through 4. The most dangerous, exotic pathogens - such as Ebola or Marburg viruses - require BSL-4 labs.
 
BSL-3 labs are required for microbes with the potential for aerosol transmission. They feature specialized ventilation systems to minimize the chances of release.
 
The diseases to be studied in the new lab could include: West Nile virus, Venezuelan equine encephalitis, hantavirus pulmonary syndrome, plague, drug-resistant tuberculosis, tularemia, glanders, melioidosis and Q fever.
 
In many cases, the studies will build on existing zoonotic-disease programs at Colorado State and its neighbor, the Centers for Disease Control and Prevention laboratory on the Foothills Campus.
 
The study of vector-borne diseases - those transmitted by mosquitoes and other insects - has been a focus of research at Colorado State and the Fort Collins CDC lab for decades.
 
"What's happened here in Fort Collins is that we probably have the strongest group of scientists in vector-borne and zoonotic diseases anywhere in the world," said Dr. Lyle Petersen, director of the CDC's Fort Collins lab.
 
Some of the bacteria and viruses to be studied in the new Colorado State BSL-3 lab are potential bioterrorism threats. Others are not.
 
West Nile virus and hantaviruses are unlikely bioweapons, for example.
 
But plague, tularemia, Venezuelan equine encephalitis, glanders, melioidosis and Q fever are considered bioterrorism threats by the U.S. government.
 
"The laboratory is being built to provide facilities that will allow this work to be done safely and securely," said Rona Hirschberg, a senior program officer at the NIAID.
 
"Many of these could be used as agents of bioterrorism and we don't, at the moment, have really good defenses against them," she said.
 
Petersen said funds from the new center will encourage drug companies to pursue vaccines that otherwise might be ignored - a new plague vaccine, for example.
 
"A vaccine company is not going to invest tens of millions of dollars into vaccine development for something with a relatively small market," Petersen said.
 
"Part of the reason for this money, actually, is to provide some federal funding for these kinds of activities," he said.
 
CSU joins eight other universities, medical schools and state health departments that won NIAID grants to establish regional biodefense and infectious disease centers.
 
"Since the 2001 anthrax attacks, the United States has been at risk for a bioterror attack," said NIAID Director Dr. Anthony Fauci. "With these grants, a key element in our strategic plan to counter bioterrorism and emerging infectious diseases is now complete."
 
The other centers are led by: University of California, Irvine; Duke University; Harvard Medical School; New York State Department of Health; University of Chicago; University of Maryland; University of Texas Medical Branch, Galveston; University of Washington; and Washington University.
 
http://www.rockymountainnews.com
 
 
Patricia A. Doyle, PhD
Please visit my "Emerging Diseases" message board.
 
Zhan le Devlesa tai sastimasa
Go with God and in Good Health

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