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Chikungunya Virus Spreads
To Malaysia, Hong Kong

From Patricia Doyle, PhD
4-3-6 
 
Chikungunya Virus Now Spread To Malaysia
 
Source: Berna News, Malaysia
April 1, 2006
 
30 People Infected By Chikungunya In Perak, Malaysia
 
 
Chikungunya, a rare mosquitoborne disease, has struck a village in Perak, and 30 cases have been detected by the Health Department since 2 weeks ago.
 
Communicable disease control director Datuk Dr Ramlee Rahmat said the Health Ministry's laboratory tests on blood samples taken from 30 villagers in Panchut, Pantai Remis confirmed that they had contracted chikungunya, a viral disease which is not life-threatening.
 
Chikungunya is an urban disease resembling dengue and is a relatively rare form of viral fever caused by an alphavirus that is spread by mosquito bites from the _Aedes_ mosquito. The name chikungunya is derived from the Swahili phrase that can be translated as "that which bends up," referring to the stooped posture that develops as a result of the arthritic symptoms of the disease.
 
"This is the 1st time that we have detected a chikungunya outbreak in this country since 1999," Dr Ramlee said when contacted on Saturday [1 Apr 2006]. The last known outbreak in Malaysia was in 1999, when 27 people were infected in Port Klang, Selangor. Chikungunya was 1st described in Tanzania, Africa in 1952.
 
Dr Ramlee said the Health Ministry was alerted to the possible outbreak 2 weeks ago, after a general practitioner (GP) in the area told the Health Department about 30 people who were found to have symptoms like those of chikungunya infection, such as fever, rashes, arthritis affecting multiple joints, as well as headache. "Following that, we went down and conducted a thorough check [in which] we took blood samples from the villagers and sent them [to] the laboratory [for] tests. After several tests, it was confirmed that they had chikungunya," he said.
 
He said the ministry believed the outbreak had occurred much earlier, as some of the villagers had been found to have similar symptoms but in smaller numbers. "Following the confirmation of the tests, we have taken action such as fogging, cleaning, as well as providing health education to the people in the affected villages," Dr Ramlee said.
 
http://www.bernama.com/bernama/v3/news_lite.php?id=189418
 
ProMED-mail
 
The current epidemic of chikungunya in the Indian Ocean basin, which started at the beginning of 2005, is actually more serious than expected. Maps of the affected area (the state of Perak, Malaysia) can be accessed at: http://malaysia.sawadee.com/perak/perak-map.htm, http://www.hoteltravel.com/malaysia/perak/maps.htm, and http://www.ait.unl.edu/doc2/students/lim/Map.htm. Perak is along peninsular Malaysia's western coast at the northern approach to the Strait of Malacca. - Mod.RY
 
 
CHIKUNGUNYA - CHINA (HONG KONG) - CONFIRMED
 
A ProMED-mail post
ProMED-mail is a program of the
International Society for Infectious Diseases
 
From: Julian W Tang
jwtang49@hotmail.com
3-31-6
 
You will be pleased to know that your recent postings of the chikungunya outbreaks in Mauritius and Reunion helped us to diagnose our 1st-ever case of chikungunya in Hong Kong SAR -- which was almost certainly imported from Mauritius.
 
A 66 year old Chinese man was seen in the Prince of Wales Hospital (PWH) Infectious Diseases clinic on 24 Mar 2006, after returning from a one-week stay in Mauritius. He attended the clinic the same day he returned to Hong Kong. He had already been ill with fever, headache, myalgia, arthralgia, and a rash for 2 days. He had been visiting relatives in rural parts of Mauritius (there is a large Chinese population there) and had been bitten by mosquitoes. The differential diagnosis was dengue fever in the first instance, but recent postings in ProMED-mail (see archive numbers: 20051231.3716, 20060121.0202, 20050519.1372) alerted us to the fact that he may also have contracted chikungunya, so this test was also requested.
 
A sample taken from this clinic visit on day 2 of illness tested positive for chikungunya by polymerase chain reaction (PCR) and confirmatory sequencing at the Public Health Laboratory Centre (PHLC). Dengue PCR, IgG and IgM testing were negative at both the PWH and PHLC diagnostic laboratories. This is the 1st case of chikungunya diagnosed in Hong Kong SAR.
 
The clinical presentations of dengue (a flavivirus) and chikungunya (an alphavirus) are very similar. The primary mosquito vector [_Aedes aegypti_] for both these viruses can be found in Hong Kong SAR, where there have been sporadic cases of dengue previously. In patients presenting with dengue-like illness, with a compatible travel history, where all dengue testing has proved negative, chikungunya may now be considered as a possible alternative diagnosis.
 
Their incubation periods may be similar (dengue 4-7 days, chikungunya 2-4 days), and both can occasionally give rise to a more severe haemorrhagic fever, though this is more common with dengue. With chikungunya, as with dengue, the viraemia is short-lived, with the virus usually only being detectable for only the first 48 hours with neutralising antibodies arising by days 5-7.
 
Chikungunya is endemic in parts of Africa and South ast Asia, including Vietnam, Thailand, Cambodia, and Burma (Myanmar). It is likely that some cases in Hong Kong may have been missed, because until now, the differential diagnosis of chikungunya may have not been considered. Chikungunya means 'bending up' in Swahili. Interestingly, the word for dengue also originates from the Swahili word 'dinga', meaning 'break-bone', due to the severe muscle and joint [pains]. This original Swahili word has been altered by the American Spanish usage (probably in South America) to 'dengue'.
_____
 
Julian Wei-Tze Tang, MA, PhD, MRCP, MRCPath, FHKCPath
Assistant Professor,
Department of Microbiology,
The Chinese University of Hong Kong,
Prince of Wales Hospital, Shatin,
New Territories, Hong Kong SAR.
jwtang49@hotmail.com
 
Dr. Julian Wei-Tze's informative feedback on the 1st imported case of CHIK in Hong Kong is indeed greatly appreciated by ProMED-Mail. ProMED-Digest presents reports on epidemic outbreaks of timely significance to all communities, including public health authorities and ordinary subscribers. The purposes of such postings are better management and understanding of any infectious diseases, either newly emerging and/or re-emerging, by responsible organizations as well as the population at large. In the current situation, many imported cases of chikungunya have been reported from a number of European countries (see also: 20060304.0695). ProMED has followed chikungunya transmission closely.
 
For interactive maps of Hong Kong: please see:
http://www.google.com/search?hl=en&q=hong+
kong+map&btnG=Google+Search
 
- Mod.RY
 
Although the main vector of chikungunya virus, _Aedes aegypti_, was previously reported in Hong Kong, it is currently reported to be absent. However, another potential vector, _Aedes albopictus_, does occur in Hong Kong. This day-biting mosquito breeds in domestic containers such as water storage pots, discarded tin cans but also in tree holes. Although transmission is possible in Hong Kong it would depend on whether breeding sites -- and thus adult mosquitoes -- were near infected people. - Mod.MS
 
 
Patricia A. Doyle DVM, PhD
Bus Admin, Tropical Agricultural Economics
Univ of West Indies
 
Please visit my "Emerging Diseases" message board at:
http://www.emergingdisease.org/phpbb/index.php
Also my new website:
http://drpdoyle.tripod.com/
Zhan le Devlesa tai sastimasa
Go with God and in Good Health
 

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