- To the European Food Safety Authority
- Since Dr. Soffritti, lead Scientist in the 36 month aspartame
study on rats rebutted EFSA's bizarre criticism of his impeccable work
there has been nothing but silence. The Ramazzini study was peer reviewed
by 7 world experts, who unquestionably know that respiratory disease is
part of the normal dying process. Dr. Soffritti's rebuttal explains:
- "As reported in a previous paper (Soffritti et al.
1999), one of the most important issues in environmental and industrial
carcinogenesis is how to deal with diffused carcinogenic risks, to which
most of the planet's population may be exposed. These carcinogenic risks
are represented by a) agents that are slightly carcinogenic at any dose;
b) low or extremely low doses of a carcinogenic agent of any kind; or c)
mixtures of small doses of carcinogenic agents.
- "Epidemiologic and experimental studies are fundamental
in the identification and quantification of diffused carcinogenic risks,
but they must be designed and conducted to be as powerful as possible with
adequate methodology. In the case of experimental studies, it is not sufficient
to follow the standard protocol used in ordinary experiments. Instead,
it is necessary to conduct studies that may be defined as "mega-experiments,"
using a vast number of animals (at least 2001,000 per experimental group)
in order to express a marked difference in the variation of effects, and
exposing the animals in all phases of development to allow the agent to
express its full carcinogenic potential.
- "It is based on this rationale that the European
Ramazzini Foundation performed a mega-experiment on 1,800 rats and demonstrated
that, in our experimental conditions, aspartame is a multipotential carcinogenic
agent (Soffritti et al. 2005; Soffritti et al. 2006).
- "The results of our study (Soffritti et al. 2005;
Soffritti et al. 2006) attracted the attention of the scientific community,
consumer and industry associations, and the national and international
agencies responsible for food safety. Among various comments, the opinion
expressed on 5 May 2006 by the European Food Safety Authority (EFSA 2006)
and the general interpretation of an epidemiologic study conducted by the
National Cancer Institute (NCI 2006) necessitate comment on our part.
- "In examining the raw data of our study, the EFSA
(2006) observed a high incidence of chronic pulmonary inflammation in males
and females in both treated groups and in the control group. Based on this
observation, it was concluded that "the increased incidence of lymphomas/leukemias
reported in treated rats was unrelated to aspartame, given the high background
incidence of chronic inflammatory changes in the lungs . . . ." In
my opinion, this conclusion is bizarre for the following reasons:
- "First, the EFSA (2006) overlooked the fact that
the study was conducted until the natural death of the rodents. IT IS WELL
KNOWN THAT INFECTIOUS PATHOLOGIES ARE PART OF THE NATURAL DYING PROCESS
IN BOTH RODENTS AND HUMANS.
- "Second, if the statistically significant increased
incidence of lymphomas/leukemias observed were indeed caused by an infected
colony, one would expect to observe an increased incidence of lymphomas/leukemias
not only in females but also in males. The EFSA (2006) did not comment
on this discrepancy in their logic.
- "Finally, in support of the hypothesis regarding
the safety of aspartame, the EFSA (2006) cited the negative results of
recent carcinogenicity studies carried out in transgenic mice by the NTP;
the ESFA did not mention that, because the NTP studies on genetically altered
mice were performed using a new experimental model, the NTP subcommittee
unanimously agreed "there is uncertainty whether the study possessed
sufficient sensitivity to detect a carcinogenic effect" (NTP 2005).
- "Interestingly, the same scrutiny applied to our
study has not been applied to a recent abstract published by Lim et al.
(2006) from the NCI diet questionnaire survey (NCI 2006) in which self-reported
aspartame consumption showed no increases in either leukemia/lymphomas
or in brain cancer. These results have been used by industry, the EFSA,
and others to argue that aspartame is not a risk for humans, in spite of
our animal study results. Without specific information on each individual's
consumption rate and duration it is difficult to assess the power of the
survey, in spite of the large number of participants. The second related
issue is whether aspartame is an early- or late-stage carcinogen. If it
is an early-stage initiator of cancer, then reporting the lack of effects
in older individuals who have not consumed aspartame since early childhood
would be expected to show little or no increased cancer (Hoel 1985).
- "The safety-in particular, the noncarcinogenicity-of
today's most widely diffused artificial sweeteners and their blends is
largely based on studies conducted decades ago. I second Karstadt's nomination
of acesulfame K for further study; however, I add that it should be evaluated
using a long-term mega-experiment.
- "The author declares he has no competing financial
- Morando Soffritti
- Cesare Maltoni Cancer Research Center
- European Foundation of Oncology and Environmental Sciences
- "B. Ramazzini"
- Bologna, Italy
- E-mail: email@example.com
- These are part of comments on a release on acesulfame
potassium, another unsafe sweetener that triggered cancer and leukemia
in original studies, that also summarize the Ramazzini Study, and the EFSA's
- Dr. Koeter, your statement" "The expertise
required [to judge any new study on whether aspartame causes cancer] almost
inevitably means having a previous involvement." You also said, "Eliminate
the scientists who had worked in the area before or who had worked for
industry and there would be no scientists left. The panel had been "fully
impartial." These statements are an abomination. You would try to
make the world believe there are no independent researchers in Europe who
are capable of reviewing an aspartame study?
- If your statement had any basis for truth, which it
doesn't, an impartial committee would look to researchers who had done
"independent" research with no financial ties to aspartame manufacturers.
Dr. Ralph Walton, for example, is an independent researcher who did a
study on aspartame. It is titled: "Adverse Reactions to Aspartame:
Double-Blind Challenge in Patients from a Vulnerable Population: http://www.mindfully.org/Health/Aspartame-Adverse-Reactions-1993.htm
Monsanto said they would provide the aspartame and then refused. Obviously,
they knew it was independent and they couldn't control it. You simply
can't test a deadly addictive excitoneurotoxic carcinogenic drug like aspartame
and not have adverse findings. And sure enough the institution had to
stop the study after one man (administrator of the hospital) had a retinal
detachment (lost his vision in one eye), one person had conjunctival bleeding,
and others reported they were being poisoned. So when Dr. John Olney,
one of the most renowned neuroscientists in the world today who founded
the field of neuroscience called excitotoxicity, made world news on the
aspartame brain tumor association, Dr. Walton appeared with him on 60 Minutes.
He did research on scientific peer reviewed studies and funding. http://www.dorway.com/peerrev.html
You will note that 92% of all independent scientific peer reviewed studies
on aspartame show the problems. And Dr. Walton notes if you remove 6 studies
the FDA had something to do with because of their controversy having to
do with aspartame manufacturers and one pro-aspartame summary, 100% of
scientific peer reviewed studies by independent studies show the problems
aspartame causes. So what does that say about studies controlled and funded
by aspartame manufacturers? To ask the question is to answer it. How
do they fix the studies?
- Scientific FAQs - Articles that detail toxicity effects
from aspartame and why industry studies find no problems.
- Heavily referenced articles.
- We expected the EFSA to sell out our health as predicted
in 2005 by Mark Gold of the Aspartame Toxicity Center,
- www.holisticmed.com/aspartame We've been seeing these
sell-outs for a quarter of a century, standard aspartame manufacturers
- "As part of a SCF 2002 review postscript I wrote
late 2005, I stated the following:
- "The European Food Safety Agency (EFSA) has stated
that it will review
- the study linking aspartame ingestion to lymphomas and
- a matter of high priority, in the context of the previous
extensive safety data available on aspartame." If that quote doesn't
give one a clue as to what the results of their review will be, I will
be more clear: The review by EFSA (industry consultants) will find no problem
with aspartame. That is a guarantee. You read it here first."
- - Mark
- We're talking about the health of the world, and what
goes on with power of the aspartame manufacturers to keep this deadly chemical
poison on the market. In fact, when the European Union was making a decision
on aspartame safety I thought it was important enough to fly to Brussels
to give them all the damning research. The first thing that happened was
I locked up for 3 1/2 hours by Immigration asking me questions like "If
we let you in England how many people will find out about the dangers of
aspartame?" They confiscated everything on aspartame I had in my
luggage but were forced to return it.
- After doing many lectures throughout England I flew to
Brussels to bring the European Union all the damning research on aspartame
during a two hour meeting. I expected they would eliminate all the serious
results and use industry fixed studies and propaganda. But they didn't
know I was wired. Here is the rebuttal to their report:
- The FDA knew aspartame was a carcinogen a quarter of
a century ago when Searle was caught excising brain tumors from rats, and
then putting them back in the study, and when they died they resurrected
them on paper. They were also caught filtering out neoplasms in an attempt
for the FDA not to see them. See the Bressler Report or FDA audit on <http://www.dorway.com/>www.dorway.com
Aspartame triggered brain, mammary, uterine, ovarian, testicular, pancreatic
and thyroid tumors.
- The Ramazzini Study just reaffirms what the FDA said
themselves from the beginning. Since a lie was used as an excuse and since
EFSA did not apologize you see the report to the International Court of
Justice, United Nations and World Health Organization. World health is
at stake with millions consuming a deadly carcinogen. We want it off the
market and we want an apology from the European Food Safety Association
for protecting industry instead of the people.
- Dr. Koeter, after writing this I see you have now owned
up to the politics involved in this article: "EU's food agency battles
attempts to hijack science."
- It says: "Science and politics make poor bedfellows.
Just ask Herman Koeter, deputy executive director at the European Food
Safety Authority (EFSA), which has felt the push and pull of national politics
ever since the agency began operating four years ago." Aspartame
was mentioned when it said: "Hot decisions that had political repercussions
included a review of a controversial aspartame study" .
- Now do something about it. Simply admit the truth and
have aspartame banned. It has been known that aspartame is a multipotential
carcinogen since the beginning. Dr. Adrian Gross, FDA toxicologist, told
Congress aspartame violated the Delaney Amendment, which says if a product
causes cancer in animals it can't be put in food. He said further without
a shadow of a doubt aspartame can produce brain tumors and brain cancer.
Nothing has changed in a quarter of a century except millions have perished
from the neurodegenerative diseases and cancers and other horrors outlined
in Dr. Roberts medical text, Aspartame Disease: An Ignored Epidemic.
Dr. Soffritti confirmed what the FDA already knew in one of the most precise
studies ever done. An apology is owed to Dr. Soffritti and to the world.
- Below my signature is the report.
- Dr. Betty Martini, D.Hum, Founder
- Mission Possible International
- 9270 River Club Parkway
- Duluth, Georgia 30097
- 770 242-2599
- Aspartame Toxicity Center
- REPORTING on The EUROPEAN FOOD SAFETY AUTHORITYS LIES
ABOUT THE RAMAZZINI ASPARTAME TOXICITY & CANCER STUDY
- To The United Nations, International Court of Justice,
World Health Organization, and Parliament:
- I'm reporting gross conflicts of interest by the European
Food Safety Authority using panel members connected to aspartame manufacturers
to judge a study adverse to the chemical. Then EFSA lied to the world by
declaring aspartame safe for human consumption.
- In original studies aspartame was identified as a trigger
of brain tumors and cancer, therefore the FDA Board of Inquiry revoked
the petition for its approval. Don Rumsfeld, then CEO of aspartame producer
G. D. Searle Co, became Reagan's Secretary of Defense, and the day after
Reagan's inauguration a new FDA Commissioner was appointed who approved
aspartame after years of FDA rejection. See the clip from the aspartame
documentary, Sweet Misery: A Poisoned World.
- Aspartame triggers mammary, uterine, ovarian, testicular,
pancreatic and thyroid tumors. In Ramazinnis 3 year study on 1,800 rats
only those fed the chemical developed malignant brain tumors. It further
triggered leukemia, lymphoma, cancer of the kidney, urethra and bladder
and peripheral nerves, especially cranial. In September of 2005 at a conference,
Dr. Soffritti, Director, declared aspartame a multipotential carcinogen,
confirming the basis for FDA rejection a quarter of a century before. After
Rumsfeld manipulated to put it on the market the FDA reversed and has been
the lackey of aspartame producers ever since, pushing pro-poison propaganda,
disregarding thousands of consumer complaints..
- We have a paper trail of official documents including
the Bressler Report, an FDA audit exposing Searle's chicanery. FDA toxicologist
Jerome Bressler declared the studies were so bad that FDA removed 20% of
his report before releasing it. Between the FDA, the aspartame industry,
their front groups hired members of the EFSA evaluating the toxicity of
- The Guardian on 5/15/06 quoted EFSA Executive Director
of the EFSA, Dr. Herman Koeter: "Dr Koeter said, he wanted to clear
up misunderstandings about "conflicts of interest" among his
advisory panel overseeing the review. MEPs complained last month that the
scientist who chairs the advisory panel, Dr Susan Barlow, works for the
International Life Sciences Institute, a body funded by sweetener manufacturers
and major aspartame users such as Coca Cola, PepsiCo and Nestle, and Monsanto.
- EFSA's conflicts of interest: One scientist in the
review had a research grant from Ajinomoto, the leading Japanese aspartame
producer. Other panel members were linked to food processors using aspartame.
But to say these scientists have conflicts of interest was misunderstanding,
Dr Koeter explained to the Rome conference.
- "The expertise required [to judge any new study
on whether aspartame causes cancer] almost inevitably means having a previous
involvement." Eliminate the scientists who had worked in the area
before or who had worked for industry and there would be no scientists
left, he said. The panel had been "fully impartial"
- He insults our intelligence. Are we to believe there
are no scientists in Europe capable of conducting this study except those
paid the aspartame industry? The one thing Dr. Koeter didn't get from the
advisory panel was impartiality. They could have mailed in their approval
on the way to cash aspartame checks.
- The panel blamed the Ramazzini cancers came from respiratory
- Dr. Morando Soffritti responded: "CHRONIC PULMONARY
INFLAMMATION IS COMMON IN THE NATURAL DYING PROCESS. MOREOVER, INFLAMMATION
WAS OBSERVED IN BOTH ANIMALS WHO WERE TREATED WITH ASPARTAME AS WELL AS
IN THE CONTROL GROUP.
- "The European Ramazzini Foundation conducts what
are known as lifespan mega-experiments, meaning that large groups of rodents
are allowed to live out their natural lifespan and are examined for histopathological
changes upon spontaneous death. This model is in contrast with most laboratories
where rodents are sacrificed at 110 weeks of age (representing about 2/3
of the lifespan). The Ramazzini study design closely mirrors the human
condition in which persons may be exposed to agents in the industrial and
general environments from embryonic life under natural death. "Since
80% of cancer is diagnosed in humans over the age of 55, it is of paramount
importance to observe how an agent affects laboratory animals in the last
third of their lives."
- Two European Parliamentarians petitioned WHO to declare
sudden death a syndrome in order to track the cases. They couldn't understand
why people are just dropping dead. Aspartame triggers an irregular heart
rhythm, interacts with cardiac medication (all drugs for that matter),
damages the cardiac conduction system and causes sudden death.
- The European Food Safety Authority will never apologize
for protecting the aspartame industry and convincing us to consume this
carcinogen. Dr. Soffritti said, "Slides of previous carcinogenesis
studies on aspartame were not reviewed by the AFC panel, ... this action
should have been obligatory in light of the European Ramazzini Foundation's
results, at the very least those involving haemopoietic and lymphoid organs
and tissues." At the highest dose level tested in the Ramazzini study,
25% of female rats bore lymphomas-leukemias compared with 8.7% in the control.
- "Because of the globalization of the industrialized
diet and the ever-increasing use of artificial sweeteners among billions
of people in both industrialized and developing countries, the European
Ramazzini Foundation considers its work on sweeteners to be of the highest
priority for the protection of public health, in particular the health
of children and pregnant women who are among the most vulnerable populations."
- Read the report to the Board of Inquiry of the FDA by
world renowned neuroscientist, Dr. John Olney, on how aspartame destroys
the brain of the fetus and children: http://www.wnho.net/dr_olney1.doc
This explains why children all over the world are suffering from autism,
ADD, ADHD and Tourettes, just for starters. Aspartame is an abortifacient
and teratogen causing birth defects and mental retardation
- The Ramazzini study results show aspartame is a carcinogen,
induces malignancies at dose levels lower than the current acceptable daily
intake for humans (40 mg/kg of body weight in the EU, 50mg/kg of body weight
in the US). Twenty years ago FFA toxicologist, Dr. Adrian Gross, testified
to Congress that FDA should not have set an allowable dose because it causes
brain tumors and cancer.
- Ajinomoto has been slithering to hide the cancer issue
from the beginning:
- Aspartame was once listed with the Pentagon in a list
of potential chemical warfare weapons.
- A recent laughable campaign to discredit the flawless
Ramazinni work proclaimed that a 10-year old "What Did You Eat Last
Year" survey sent out by AARP that mentioned it once in 56 questions
proves its safe. Mother Goose! It got tremendous press, after all who
gets their advertising dollars?
- Three congressional hearings. Medical texts like Aspartame
Disease: An Ignored Epidemic by H. J. Roberts, M.D., www.sunsentpress.com
and Excitotoxins: The Taste That Kills by neurosurgeon Russell Blaylock,
M.D. explain in technical and irrefutable detail the symptoms of this
global plague. Google has 3 million web sites, most exposing aspartame
- The Idaho Observer has just released their dynamite Save
our Children! Document for parents, educators, Boards of Education, Pediatricians
& OB-GYN's exposing this deadly threat to our children's futures. and
survival on Aspartame Awareness Weekend, Sept 9th and 10th, and Save the
Children. www.idaho-observer.com Aspartame Disease will be known as one
of the great plagues in history with millions of unwarned innocent victims
slowly and inevitably damaged and destroyed. It skews DNA, threatening
our race. We ask you to help by distributing the school brochure to educators
and public organizations in your area.
- Herman Koeter and his comprised panel must resign. Demand
the truth for yourself and the world. The 90 minute aspartame documentary
is perfectly named: Sweet Misery: A Poisoned World..
- Dr. Betty Martini, D.Hum, Founder
- Mission Possible International
- 9270 River Club Parkway
- Duluth, Georgia 30097
- 770 242-2599
- www.wnho.net and
- www.mpwhi.net under construction