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The Cause Of Crohn's,
IBS And Most Colitis

By Jeff Rense
One of the most crucial missions of rense.com is to stop the beef and dairy poisoning - and deaths - of untold millions of Americans. The massive consumption of these 'products' leads inevitably to the countless numbers of health breakdowns and diseases...everything from cancer to heart disease to Crohn's, IBS and colitis...which are ravaging what's left of this faltering society.

MAP (mycobacterium paratubercolosis) in beef and all dairy products is the primary cause of MOST Crohn's, IBS and colitis.  MAP is projected to infect about a third of US dairy and beef herds.
"I am absolutely certain that some strains of MAP can be pathogenic for humans and can cause Crohn's disease in susceptible people. Since MAP is known to be a primary specific cause of chronic inflammation of the intestine in many different species, including primates, it would be remarkable if it did not cause disease in humans."  -John Hermon-Taylor, Professor, St. George's Medical School, London, England and a leading world expert on Crohn's Disease.
And now read this...
"Since Crohn's disease was first recognised in the early part of the twentieth century, it has been theorised that the disease is caused by a bacterial infection, with the principal suspect being mycobacteria, and more specifically in recent times, Mycobacterium paratuberculosis. Recently, research is making advances in understanding this organism, and is indicating more and more that at least some cases of Crohn's disease, if not all, are caused by paratuberculosis infection. Most importantly, the majority of Crohn's patients treated with antibiotic treatment which has activity against Mycobacterium paratuberculosis go into clinical remission.
This is important information for sufferers of Crohn's disease, because Mycobacterium paratuberculosis is endemic in foods derived from cattle in most areas of the western world. Mycobacterium paratuberculosis causes a chronic Inflammatory Bowel Disease in cattle, and many other species, which is similar to Crohn's disease. In some countries, the percentage of cattle herds infected with Mycobacterium paratuberculosis is extemely high. In the United States, 40% of large dairy herds are infected with Mycobacterium paratuberculosis.
Mycobacterium paratuberculosis is present in the milk, faeces and meat of infected cattle. There is a large body of evidence which indicates that Mycobacterium paratuberculosis is not killed by the standard food processing techniques that we rely on to protect us from disease-causing bacteria, such as pasteurization and cooking. Mycobacterium paratuberculosis may also be present in water supplies in areas where the faeces of infected cattle wash into the water supply, and standard water treatment methods do not kill it.
Up to now, the beef and dairy industries have preferred to defer action on removing Mycobacterium paratuberculosis from herds of food animals until it is proven that Mycobacterium paratuberculosis causes disease in humans. That proof has now arrived. In February 1998, a paper was published in the British Medical Journal which documented the first proven case of M. paratuberculosis causing disease in a human being. The patient, a seven year old boy, developed a M. paratuberculosis infection in the lymph nodes of his neck. This was followed, after a five year incubation period, by an intestinal disease that was indistinguishable from Crohn's disease. See Mycobacterium paratuberculosis Cervical Lymphadenitis followed five years later by terminal ileitis similar to Crohn's Disease for more details."
(from http://alan.kennedy.name/crohns/welcome.htm)
So, you see, the answer to Crohn's, in most cases, is proven and profoundly obvious. M. Paratuberculosis is a killer and it is found in beef flesh and dairy products. And the world needs to know.  STOP eating MEAT and STOP eating DAIRY.
By the way...Mad Cow Disease - does the USDA care? Forget about it.
The USDA would only check about 23,000 out of 32 MILLION cattle slaughtered and eaten every year for mad cow disease...because they KNOW it is common in US cattle. It is so common, the USDA announced about a year ago that it is REDUCING the number of cattle tested yearly by NINETY PERCENT to something like 2,300. Reducing the number of cattle tested to a fly-speck in number tells the story, loud and clear.
And then there are the two US slaughterhouses which each built on-premesis labs so they could test EACH cow processed for mad cow disease.  It's the LAW in Japan, by the way.In both cases, the USDA essentially said, "Try it and you're out of business" and blocked them from testing their cattle.
In fact, the Bush administration is now fighting to PREVENT the testing for mad cow disease in the U.S. Don't believe it? Read on...
Americans are being sacrificed...murdered...to protect the beef and dairy industries.
Crohn's, IBS and colitis is caused by MAP in beef flesh and in dairy products.  End of story.
Alan Cantwell, MD
Hi Jeff -
Congrats on your paper.......there have been reports of mycobacterial infection as a cause of Crohn's disease for decades. [http://www.rense.com/general77/croh.htm]
One wonders why it takes so many years for "medical science" to prove or disprove this research. I suspect "ignorance is bliss" in science as it certainly is much more lucrative to treat a disease in which little is known about the cause -- in comparison of the cost savings when the cause is known!!
(There are 129 citations relating to "M. paratuberculosis and Crohn's disease on the PubMed website -- dating back to the 1980s.)
I strongly suspect the ultimate "proof" of mycobacteria in this disease and other closely related gastrointestinal diseases is being delayed because the implication of infected meat and dairy is "politically incorrect." The same situation holds for the finding of acid-fast mycobacteria in cancer, etc.
I find it amazing that so-called "conspiracy websites", such as rense.com, seem to contain more important "science" than is found in most medical journals nowadays.
Keep on educating your readers to important research that needs to be exposed to the public.
PS: Below is just one example of the validity of up-to-date research connecting bacteria to Crohn's.
1: Epidemiol Infect. 2007 Apr 20;:1-12 [Epub ahead of print]?Links
Epidemiological evidence for Mycobacterium avium subspecies paratuberculosis as a cause of Crohn's disease.
Uzoigwe JC, Khaitsa ML, Gibbs PS.
Department of Chemistry, Biochemistry and Molecular Biology, North Dakota State University, Fargo, ND, USA.
Mycobacterium avium subspecies paratuberculosis is the causative agent of Johne's disease, a chronic enteritis in ruminants including cattle, sheep, goats, and farmed deer. Recently, this bacterium has received an increasingly wide interest because of a rapidly growing body of scientific evidence which suggests that human infection with this microorganism may be causing some, and possibly all, cases of Crohn's disease. Recent studies have shown that a high percentage of people with Crohn's disease are infected with M. avium subsp. paratuberculosis; whether the association of this bacterium and Crohn's disease is causal or coincidental is not known. Crohn's disease is a gastrointestinal disease in humans with similar histopathological findings to those observed in the paucibacillary form of Johne's disease in cattle. The search for risk factors in Crohn's disease has been frustrating. However, epidemiologists have gathered enough information that points to an association between M. avium subsp. paratuberculosis and Crohn's disease. This paper reviews epidemiological models of disease causation, the major philosophical doctrines about causation, the established epidemiological criteria for causation, and the currently known epidemiological evidence of M. avium subsp. paratuberculosis as a possible cause of Crohn's disease.
PMID: 17445316 [PubMed - as supplied by publisher]
Alan Cantwell M.D.
From: Alan Cantwell MD
Date: June 18, 2007
To: David Russell MD
Subject: Read your article on rense about crohn's and mycobacteria
On Jun 18, 2007, at 6:53 PM, David Russell wrote:
Interesting article and I do believe that crohn's has a bacterial component.
What drugs are good for use against m. paratuberculosis?
David N Russell MD
Hello Dr Russell
I don't think I can answer that.
I would imagine that M. para-tb would be difficult to treat (with a specific antibiotic) under any circumstances.
Apparently it is hard to treat in animals (see abstract below)
Also below is some info from a vet group
Best regards,
Alan Cantwell
PS: because the antibiotic therapy is so difficult, it would be good to suggest a meat and dairy free diet for a few weeks and see what happens-- as Jeff Rense suggests.
Vet Microbiol. 2004 Dec 9;104(3-4):143-55.
Related Articles, Links?
An evaluation of mycophage therapy, chemotherapy and vaccination for control of Mycobacterium avium subsp. paratuberculosis infection.
Emery DL, Whittington RJ.
Faculty of Veterinary Science, University of Sydney Locked Bag 3, Camden, NSW 2570, Australia. david.emery@camden.usyd.edu.au
The control of ovine Johne's disease (OJD) is important for domestic trade, the viability of farming units and possibly also for public health. Current strategies in Australia have included quarantine and pasture spelling to decrease prevalence and shedding rates and reduce numbers of Mycobacterium paratuberculosis (Mptb) ingested by susceptible sheep. However, alternative procedures are needed and vaccination with Gudair has recently commenced. This review examines prospects for the control of OJD by chemotherapy, vaccination and mycophages. Current chemotherapeutic regimes for treatment of M. paratuberculosis in ruminants are prohibitively expensive and of dubious efficacy, and apart from environmental concerns, mycophage therapy lacks a track record of success against intracellular bacteria. There is substantial evidence that live and killed mycobacterial vaccines reduce the incidence of clinical disease and shedding rates in OJD. An appraisal of recent experimental results suggests that neonatal vaccination with a defined dose of M. paratuberculosis offers the best prospects for the induction of protective Th1-type immunity.
Publication Types:
· Research Support, Non-U.S. Gov't
· Review
PMID: 15564023 (PubMed - indexed for MEDLINE)
M. paratuberculosis is naturally resistant to many commonly used antimicrobial drugs.
Information about the susceptibility of M. paratuberculosis to antimicrobial drugs is minimal. This is largely because treatment of animals with Johne's disease is considered to be too costly.
Drug susceptibility in vitro
M. paratuberculosis has not heretofore been considered a human pathogen. For a review of this issue please visit the page of this website called "Zoonotic potential". However, treatment of Chron's disease patients for M. Paratuberculosis has been tried and results of such studies are described on that page.
It has not been considered economically prudent to treat animals with Johne's disease. The chances of curing the animal are low, the cost of the drugs is high and the meat and milk derived from animals treated with the kind of potent drugs required are not suitable for human consumption. Hence, very little research has been done to establish a profile of drug susceptibility based on laboratory tests (i.e. in vitro drug susceptibility testing).
What can be gleaned from the few published reports can be loosely summarized as follows:
Drug class or group
Drugs tested in this group
M. paratuberculosis susceptibility based on in vitro data
First line TB drugs*
Rifampicin, Ethambutol, Isoniazid, Pyrazinamide
ofloxacin, ciprofloxacin
*TB refers to tuberculosis in humans caused by Mycobacterium Tuberculosis.
Readers should understand the many shortcomings of this table:
1) the table is based on very limited amounts of data from different sources and not all of it is consistent.
2) there are antibiotic susceptibility differences among M. paratuberculosis strains.
3) methods for performing drug susceptibility studies on a pathogen that grows so slowly are not well developed.
4) in vitro tests on mycobacteria are notoriously poor at predicting treatment efficacy in vivo (meaning what is predicted to work based on laboratory tests often fails in patients).
Animal treatment
The most comprehensive review of this topic was written by Guy St, Jean (The Veterinary Clinics of North America - Food, volume 12, pages 417-430, July, 1996). The most recent report of attempted treatment of a cow with Johne's disease is found on pages 56-60 of the Proceedings of the 34th Annual Convention of the American Association of Bovine Practitioners, September 13-15, 2001.
The conclusion from both the review and the recent single case study is that therapy for clinical paratuberculosis in cattle is costly, inconvenient (requires daily medication) and produces remission of clinical signs only, not elimination of the infection. Once treatment stops, the signs of the infection return since the infection was not cured. Costs to treat a 550 Kg cow range from roughly US$1/day for isoniazid to over US$200/day for amikacin. Given that treatment must continue for at least 6 months and that the economic value of most cows is only US$1,000 - US$2,000, it is seldom financially rational to treat cattle with paratuberculosis. In addition, meat and milk from treated cows legally can not be used for human consumption. The one situation where treatment may be useful is to maintain genetically valuable cow long enough to recover embryos.
Alan Cantwell M.D.



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